The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

Asher Ornoy; Naama Zvi; Judy Arnon; Rebecka Wajnberg; Svetlana Shechtman; Orna Diav-Citrin

doi:10.1016/j.reprotox.2008.03.001

The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

Asher Ornoy
, Naama Zvi
, Judy Arnon
, Rebecka Wajnberg
, Svetlana Shechtman
, Orna Diav-Citrin

פרסום מחקרי: פרסום בכתב עת › מאמר › ביקורת עמיתים

62 ציטוטים ‏(Scopus)

תקציר

In spite of a substantial increase in the use of topiramate at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 52 pregnancies with 41 liveborn infants from which it seems that topiramate reduces birth weight without decreasing gestational age at delivery, but does not seem to increase the risk for structural defects. There was an increased rate of spontaneous abortions not related to the drug effects.

שפה מקורית	אנגלית
עמודים (מ-עד)	388-389
מספר עמודים	2
כתב עת	Reproductive Toxicology
כרך	25
מספר גיליון	3
מזהי עצם דיגיטלי (DOIs)	https://doi.org/10.1016/j.reprotox.2008.03.001
סטטוס פרסום	פורסם - אפר׳ 2008
פורסם באופן חיצוני	כן

גישה למסמך

10.1016/j.reprotox.2008.03.001

קבצים וקישורים אחרים

Link to publication in Scopus

פורמט ציטוט ביבליוגרפי

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title = "The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies",

abstract = "In spite of a substantial increase in the use of topiramate at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 52 pregnancies with 41 liveborn infants from which it seems that topiramate reduces birth weight without decreasing gestational age at delivery, but does not seem to increase the risk for structural defects. There was an increased rate of spontaneous abortions not related to the drug effects.",

keywords = "Congenital anomalies, Pregnancy, Spontaneous abortions, Topiramate",

author = "Asher Ornoy and Naama Zvi and Judy Arnon and Rebecka Wajnberg and Svetlana Shechtman and Orna Diav-Citrin",

year = "2008",

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doi = "10.1016/j.reprotox.2008.03.001",

language = "אנגלית",

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T2 - A study on 52 pregnancies

AU - Ornoy, Asher

AU - Zvi, Naama

AU - Arnon, Judy

AU - Wajnberg, Rebecka

AU - Shechtman, Svetlana

AU - Diav-Citrin, Orna

PY - 2008/4

Y1 - 2008/4

N2 - In spite of a substantial increase in the use of topiramate at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 52 pregnancies with 41 liveborn infants from which it seems that topiramate reduces birth weight without decreasing gestational age at delivery, but does not seem to increase the risk for structural defects. There was an increased rate of spontaneous abortions not related to the drug effects.

AB - In spite of a substantial increase in the use of topiramate at child bearing age, very little is known regarding its use in pregnancy. We describe the outcome of 52 pregnancies with 41 liveborn infants from which it seems that topiramate reduces birth weight without decreasing gestational age at delivery, but does not seem to increase the risk for structural defects. There was an increased rate of spontaneous abortions not related to the drug effects.

KW - Congenital anomalies

KW - Pregnancy

KW - Spontaneous abortions

KW - Topiramate

UR - https://www.scopus.com/pages/publications/44149124250

U2 - 10.1016/j.reprotox.2008.03.001

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IS - 3

ER -

The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

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