Prevalence of Paroxysmal Nocturnal Hemoglobinuria Clones in Myeloproliferative Neoplasm Patients: A Cross-Sectional Study

Odit Gutwein; Yoav Englander; Katrin Herzog-Tzarfati; Talia Filipovich-Rimon; Arie Apel; Ronit Marcus; Naomi Rahimi-Levene; Maya Koren-Michowitz

doi:10.1016/j.clml.2019.07.441

Prevalence of Paroxysmal Nocturnal Hemoglobinuria Clones in Myeloproliferative Neoplasm Patients: A Cross-Sectional Study

Odit Gutwein
, Yoav Englander
, Katrin Herzog-Tzarfati
, Talia Filipovich-Rimon
, Arie Apel
, Ronit Marcus
, Naomi Rahimi-Levene
, Maya Koren-Michowitz

פרסום מחקרי: פרסום בכתב עת › מאמר › ביקורת עמיתים

8 ציטוטים ‏(Scopus)

תקציר

Paroxysmal nocturnal hemoglobinuria (PNH) and myeloproliferative neoplasm (MPN) are diseases associated with increased thrombosis. PNH clones are commonly found in other hematologic diseases, such as myelodysplastic syndromes and aplastic anemia. The presence of PNH clones was studied in consecutive MPN patients. A prevalence of 2% and an association with the JAK2 mutation was found. Presence of a PNH clone could potentially influence the clinical course of MPN.

שפה מקורית	אנגלית
עמודים (מ-עד)	812-814
מספר עמודים	3
כתב עת	Clinical Lymphoma, Myeloma and Leukemia
כרך	19
מספר גיליון	12
מזהי עצם דיגיטלי (DOIs)	https://doi.org/10.1016/j.clml.2019.07.441
סטטוס פרסום	פורסם - דצמ׳ 2019
פורסם באופן חיצוני	כן

גישה למסמך

10.1016/j.clml.2019.07.441

קבצים וקישורים אחרים

Link to publication in Scopus

פורמט ציטוט ביבליוגרפי

@article{2393c5328f1042168bfd6daf12c3a167,

title = "Prevalence of Paroxysmal Nocturnal Hemoglobinuria Clones in Myeloproliferative Neoplasm Patients: A Cross-Sectional Study",

abstract = "Paroxysmal nocturnal hemoglobinuria (PNH) and myeloproliferative neoplasm (MPN) are diseases associated with increased thrombosis. PNH clones are commonly found in other hematologic diseases, such as myelodysplastic syndromes and aplastic anemia. The presence of PNH clones was studied in consecutive MPN patients. A prevalence of 2\% and an association with the JAK2 mutation was found. Presence of a PNH clone could potentially influence the clinical course of MPN.",

keywords = "Clones, JAK2 V617F, MPN, PNH",

author = "Odit Gutwein and Yoav Englander and Katrin Herzog-Tzarfati and Talia Filipovich-Rimon and Arie Apel and Ronit Marcus and Naomi Rahimi-Levene and Maya Koren-Michowitz",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = dec,

doi = "10.1016/j.clml.2019.07.441",

language = "אנגלית",

volume = "19",

pages = "812--814",

journal = "Clinical Lymphoma, Myeloma and Leukemia",

issn = "2152-2650",

publisher = "Elsevier Inc.",

number = "12",

}

Gutwein, O, Englander, Y, Herzog-Tzarfati, K, Filipovich-Rimon, T, Apel, A, Marcus, R, Rahimi-Levene, N & Koren-Michowitz, M 2019, 'Prevalence of Paroxysmal Nocturnal Hemoglobinuria Clones in Myeloproliferative Neoplasm Patients: A Cross-Sectional Study', Clinical Lymphoma, Myeloma and Leukemia, כרך 19, מס' 12, עמודים 812-814. https://doi.org/10.1016/j.clml.2019.07.441

Prevalence of Paroxysmal Nocturnal Hemoglobinuria Clones in Myeloproliferative Neoplasm Patients: A Cross-Sectional Study. / Gutwein, Odit; Englander, Yoav; Herzog-Tzarfati, Katrin et al.
ב-: Clinical Lymphoma, Myeloma and Leukemia, כרך 19, מס' 12, 12.2019, עמוד 812-814.

פרסום מחקרי: פרסום בכתב עת › מאמר › ביקורת עמיתים

TY - JOUR

T1 - Prevalence of Paroxysmal Nocturnal Hemoglobinuria Clones in Myeloproliferative Neoplasm Patients

T2 - A Cross-Sectional Study

AU - Gutwein, Odit

AU - Englander, Yoav

AU - Herzog-Tzarfati, Katrin

AU - Filipovich-Rimon, Talia

AU - Apel, Arie

AU - Marcus, Ronit

AU - Rahimi-Levene, Naomi

AU - Koren-Michowitz, Maya

PY - 2019/12

Y1 - 2019/12

N2 - Paroxysmal nocturnal hemoglobinuria (PNH) and myeloproliferative neoplasm (MPN) are diseases associated with increased thrombosis. PNH clones are commonly found in other hematologic diseases, such as myelodysplastic syndromes and aplastic anemia. The presence of PNH clones was studied in consecutive MPN patients. A prevalence of 2% and an association with the JAK2 mutation was found. Presence of a PNH clone could potentially influence the clinical course of MPN.

AB - Paroxysmal nocturnal hemoglobinuria (PNH) and myeloproliferative neoplasm (MPN) are diseases associated with increased thrombosis. PNH clones are commonly found in other hematologic diseases, such as myelodysplastic syndromes and aplastic anemia. The presence of PNH clones was studied in consecutive MPN patients. A prevalence of 2% and an association with the JAK2 mutation was found. Presence of a PNH clone could potentially influence the clinical course of MPN.

KW - Clones

KW - JAK2 V617F

KW - MPN

KW - PNH

UR - https://www.scopus.com/pages/publications/85072999616

U2 - 10.1016/j.clml.2019.07.441

DO - 10.1016/j.clml.2019.07.441

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 31601527

AN - SCOPUS:85072999616

SN - 2152-2650

VL - 19

SP - 812

EP - 814

JO - Clinical Lymphoma, Myeloma and Leukemia

JF - Clinical Lymphoma, Myeloma and Leukemia

IS - 12

ER -

Prevalence of Paroxysmal Nocturnal Hemoglobinuria Clones in Myeloproliferative Neoplasm Patients: A Cross-Sectional Study

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