Prenatal multivitamins containing folic acid do not decrease prevalence of depression among pregnant women

Y. J. Cho, J. Y. Han, J. S. Choi, H. K. Ahn, H. M. Ryu, M. Y. Kim, J. H. Yang, A. A. Nava-Ocampo, G. Koren

פרסום מחקרי: פרסום בכתב עתמאמרביקורת עמיתים

19 ציטוטים ‏(Scopus)

תקציר

Several studies have reported an association between depression and folic acid deficiency. We investigated whether intake of prenatal multivitamins containing folic acid (MVandFA) was associated with decreased rates of depression among pregnant women. A questionnaire was given to 1,314 low-risk pregnant women. Of them, 1,277 (97.2%) women completed the questionnaire. The overall prevalence of depression was 8.1%. Of 652 participants who did not take MVandFA, 9.4% had depression, whereas 6.9% of 624 women who had MVandFA had depression (p = 0.11). In a multivariate logistic regression analysis, family history of depression (adjusted OR 3.7; 95% CI 1.9-7.3) and premenstrual syndrome (adjusted OR 3.0, 95% CI 1.8-4.8) were identified as risk factors for depression during pregnancy. In conclusion, intake of MVandFA was not associated with lower rates of depression during pregnancy whereas family history of depression and personal history of premenstrual syndrome were significant risk factors.

שפה מקוריתאנגלית
עמודים (מ-עד)482-484
מספר עמודים3
כתב עתJournal of Obstetrics and Gynaecology
כרך28
מספר גיליון5
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - יולי 2008
פורסם באופן חיצוניכן

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