TY - JOUR
T1 - Pheochromocytoma induced fulminant cardiogenic shock following laparoscopic salpingectomy, successfully managed with extracorporeal membrane oxygenation
AU - Ezri, Tiberiu
AU - Golan, Abraham
AU - Sasson, Lior
AU - Rozenman, Yoseph
PY - 2009/10
Y1 - 2009/10
N2 - Pheochromocytoma is a rare disorder caused by functioning tumor composed of chromaffin cells that secrete catecholamines. Patients with undiagnosed pheochromocytoma may have a high mortality. We present a young female patient with a preoperative diagnosis of asymptomatic neurofibromatosis who underwent laparoscopic salpyngectomy for ectopic pregnancy. She subsequently developed a severe acute catecholamine-induced toxic cardiomyopathy presenting with cardiogenic and noncardiogenic pulmonary edema and shock. Intra-aortic balloon pump (IABP) support, combined with inotropic therapy, was unsuccessful in restoring hemodynamic stability. As a desperate measure, the patient was connected to an extracorporeal membrane oxygenation (ECMO) device. Within a few days, her condition gradually improved and she was weaned from ECMO and mechanical ventilation. A left adrenal pheochromocytoma was subsequently diagnosed and successfully removed laparoscopically, after two weeks of patient preparation. The patient was discharged home with no serious complications. We discuss the clinical presentation and treatment of catecholamine-induced cardiomyopathy.
AB - Pheochromocytoma is a rare disorder caused by functioning tumor composed of chromaffin cells that secrete catecholamines. Patients with undiagnosed pheochromocytoma may have a high mortality. We present a young female patient with a preoperative diagnosis of asymptomatic neurofibromatosis who underwent laparoscopic salpyngectomy for ectopic pregnancy. She subsequently developed a severe acute catecholamine-induced toxic cardiomyopathy presenting with cardiogenic and noncardiogenic pulmonary edema and shock. Intra-aortic balloon pump (IABP) support, combined with inotropic therapy, was unsuccessful in restoring hemodynamic stability. As a desperate measure, the patient was connected to an extracorporeal membrane oxygenation (ECMO) device. Within a few days, her condition gradually improved and she was weaned from ECMO and mechanical ventilation. A left adrenal pheochromocytoma was subsequently diagnosed and successfully removed laparoscopically, after two weeks of patient preparation. The patient was discharged home with no serious complications. We discuss the clinical presentation and treatment of catecholamine-induced cardiomyopathy.
KW - Anesthesia
KW - Cardiopulmonary failure
KW - Extracorporeal membrane oxygenator
KW - Pheochromocytoma
KW - Salpingectomy
UR - http://www.scopus.com/inward/record.url?scp=77953395320&partnerID=8YFLogxK
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AN - SCOPUS:77953395320
SN - 2344-2336
VL - 16
SP - 154
EP - 158
JO - Jurnalul Roman de Anestezie Terapie Intensiva
JF - Jurnalul Roman de Anestezie Terapie Intensiva
IS - 2
ER -