TY - JOUR
T1 - Outcome of carbapenem resistant Klebsiella pneumoniae bloodstream infections
AU - Ben-David, D.
AU - Kordevani, R.
AU - Keller, N.
AU - Tal, I.
AU - Marzel, A.
AU - Gal-Mor, O.
AU - Maor, Y.
AU - Rahav, G.
PY - 2012/1
Y1 - 2012/1
N2 - The aim of this study was to evaluate the impact of carbapenem-resistant K. pneumoniae bloodstream infections on mortality. During the study period 42, 68 and 120 patients were identified with carbapenem-resistant, extended-spectrum β-lactamase producers (ESBL) and susceptible K. pneumoniae bloodstream infections, respectively. Patients with carbapenem-resistant K. pneumoniae had higher rates of prior antimicrobial exposure, other nosocomial infections, and use of invasive devices. Infection-related mortality was 48% for carbapenem-resistant, 22% for ESBL producers and 17% for susceptible K. pneumoniae. Independent risk factors for infection-related mortality were Pitt bacteraemia score, Charlson score and carbapenem resistance.
AB - The aim of this study was to evaluate the impact of carbapenem-resistant K. pneumoniae bloodstream infections on mortality. During the study period 42, 68 and 120 patients were identified with carbapenem-resistant, extended-spectrum β-lactamase producers (ESBL) and susceptible K. pneumoniae bloodstream infections, respectively. Patients with carbapenem-resistant K. pneumoniae had higher rates of prior antimicrobial exposure, other nosocomial infections, and use of invasive devices. Infection-related mortality was 48% for carbapenem-resistant, 22% for ESBL producers and 17% for susceptible K. pneumoniae. Independent risk factors for infection-related mortality were Pitt bacteraemia score, Charlson score and carbapenem resistance.
KW - Bloodstream infection
KW - Carbapenem resistance
KW - Klebsiella pneumoniae
KW - Outcome
UR - http://www.scopus.com/inward/record.url?scp=83655201460&partnerID=8YFLogxK
U2 - 10.1111/j.1469-0691.2011.03478.x
DO - 10.1111/j.1469-0691.2011.03478.x
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 21722257
AN - SCOPUS:83655201460
SN - 1198-743X
VL - 18
SP - 54
EP - 60
JO - Clinical Microbiology and Infection
JF - Clinical Microbiology and Infection
IS - 1
ER -