Long-term outcome of infective endocarditis: The impact of early surgical intervention

Jihad Bishara, Leonard Leibovici, Dina Gartman Gartman-Israel, Alex Sagie, Arkadi Kazakov, Eugeni Miroshnik, Shai Ashkenazi, Silvio Pitlik

פרסום מחקרי: פרסום בכתב עתמאמרביקורת עמיתים

91 ציטוטים ‏(Scopus)

תקציר

To determine the impact of early surgical intervention on long-term survival in patients with infective endocarditis (IE), charts of all patients who had IE from January 1987 through December 1996 were reviewed. A total of 252 patients with definite or possible IE were included. Forty-four patients (17.5%) had early surgery on median hospital day 2 (range, 0-30 days), and 208 patients (82.5%) received medical treatment alone. On multivariate analysis, several variables, including early surgical intervention, improved long-term survival rates (hazard ratio, 1.5; P = .03), mainly in patients with Staphylococcus aureus etiology (P = .04). When patients with prosthetic devices were excluded, the median duration of survival for patients who had early surgery was >150 months, compared with 61.5 months for patients in the medical group (P = .1). Early surgical intervention compared with medical therapy alone is associated with increased short- and long-term survival rates in patients with IE, primarily when IE is caused by S. aureus.

שפה מקוריתאנגלית
עמודים (מ-עד)1636-1643
מספר עמודים8
כתב עתClinical Infectious Diseases
כרך33
מספר גיליון10
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - 15 נוב׳ 2001
פורסם באופן חיצוניכן

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