תקציר
QUESTION: A patient of mine has been prescribed letrozole to induce ovulation; however, a recent release from the Food and Drug Administration contraindicates the use of letrozole in premenopausal women owing to teratogenicity. Does the use of letrozole increase the risk of a child being born with a birth defect? ANSWER: The use of letrozole to induce ovulation has not been associated with an increased risk of a child being born with a birth defect; in contrast, the use of clomiphene citrate in pregnancy is associated with intrauterine growth restriction.
שפה מקורית | אנגלית |
---|---|
עמודים (מ-עד) | 353-354 |
מספר עמודים | 2 |
כתב עת | Canadian Family Physician |
כרך | 54 |
מספר גיליון | 3 |
סטטוס פרסום | פורסם - מרץ 2008 |
פורסם באופן חיצוני | כן |