Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury

Keyphrases

• Small Interfering RNA (siRNA) 100%
• Phosphatase 100%
• Spinal Cord Compression 100%
• MSC-Exo 100%
• Intranasal Delivery 100%
• Mesenchymal Stem Cell-derived Exosomes 100%
• Tensin Homolog 100%
• Spinal Cord Injury 66%
• Intranasal 66%
• Injured Spinal Cord 66%
• Blood-brain Barrier 33%
• Mesenchymal Stem Cells 33%
• Spontaneous Recovery 33%
• Neovascularization 33%
• Functional Recovery 33%
• Therapeutic Efficacy 33%
• Axonal Growth 33%
• Intranasal Administration 33%
• Astrogliosis 33%
• Structural Function 33%
• Microgliosis 33%
• Permanent Neurological Deficits 33%
• Electrophysiological Function 33%
• Region Following 33%
• Exosomes 33%

Neuroscience

• Mesenchymal Stem Cell 100%
• Phosphatase 100%
• Spinal Cord Injury 100%
• Small Interfering RNA 100%
• Tensin 100%
• Blood Brain Barrier 25%
• Astrogliosis 25%
• Gliosis 25%

Immunology and Microbiology

• Mesenchymal Stem Cell 100%
• Spinal Cord 100%
• Exosome 100%
• Neovascularization (Pathology) 16%
• Blood Brain Barrier 16%