Hypothyroidism in Young Children Following Exposure to Iodinated Contrast Media: An Observational Study and a Review of the Literature

Vered Rosenberg, Alexander Michel, Gabriel Chodick, Yingkai Cheng, Petra Palkowitsch, Gideon Koren, Varda Shalev

פרסום מחקרי: פרסום בכתב עתמאמרביקורת עמיתים

3 ציטוטים ‏(Scopus)

תקציר

While it is well documented that exposure to iodinated contrast media (ICM) can interfere with thyroid function in adults, much less is known about the incidence and risk factors associated with ICM induced hypothyroidism in young children. Using a computerized database we identified 843 children who were exposed to ICM between 1998 and 2015. The incidence rate of ICM induced hypothyroidism per 1000 person-years was 9.66 (95% CI: 4.17-19.04). When compared to the rest of the cohort, children with hypothyroidism were more likely to be younger, weigh less and to have undergone cardio-angiography. These results are supported by findings described in the literature review. The risk of ICM- induced hypothyroidism needs to be considered especially in young children with low weight, undergoing cardio-angiography examinations. Systematic monitoring of thyroid function should be conducted in this focused patient population to avoid potential adverse consequences on child development.

שפה מקוריתאנגלית
עמודים (מ-עד)256-265
מספר עמודים10
כתב עתPediatric Endocrinology Reviews
כרך16
מספר גיליון2
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - 1 דצמ׳ 2018
פורסם באופן חיצוניכן

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