HSP72 depletion suppresses γh2AX activation by genotoxic stresses via p53/p21 signaling

Keyphrases

• HSP72 100%
• Genotoxic Stress 100%
• H2AX 83%
• DNA Damage 50%
• Insults 33%
• DNA Damage Response 33%
• Heat Shock Proteins 16%
• Senescence 16%
• Signaling Pathway 16%
• DNA Repair 16%
• High Sensitivity 16%
• Knockdown 16%
• Doxorubicin 16%
• Phosphorylated Forms 16%
• Histone H2AX 16%
• Dephosphorylation 16%
• Positive Feedback Loop 16%
• Chromosomal Instability 16%
• MDC1 16%
• P53 Pathway 16%
• Mouse Embryonic Fibroblasts 16%
• Decreased Expression 16%
• Human Tumor Cells 16%
• Radiation Focusing 16%
• Radiation Sensitivity 16%

Biochemistry, Genetics and Molecular Biology

• P21 100%
• P53 100%
• DNA Damage 40%
• DNA Damage Response 40%
• Heat Shock Protein 20%
• Downregulation 20%
• Signal Transduction 20%
• DNA Repair 20%
• Sensitization 20%
• Dephosphorylation 20%
• Radiosensitivity 20%
• Chromosome Instability 20%
• Positive Feedback 20%
• MDC1 20%
• Histone 20%
• Doxorubicin 20%
• Fibroblast 20%