Cannabinoid Receptor 2 Blockade Prevents Anti-Depressive-like Effect of Cannabidiol Acid Methyl Ester in Female WKY Rats

Pharmacology, Toxicology and Pharmaceutical Science

• Disease 100%
• Antidepressant 100%
• Cannabidiol 100%
• Major Depression 100%
• Endocannabinoid 100%
• Brain Derived Neurotrophic Factor 100%
• Cannabinoid 2 Receptor 100%
• Fatty Acid Amidase 100%
• Preclinical Study 50%
• Pathophysiology 50%
• Endocannabinoid System 50%
• Receptor Antagonist 50%

Keyphrases

• Cannabidiol 100%
• Depressive-like Behavior 100%
• Methyl Ester 100%
• Cannabinoid Receptor 2 100%
• Cannabidiolic Acid 87%
• Forced Swim Test 37%
• Major Depressive Disorder 25%
• Brain-derived Neurotrophic Factor 25%
• Antidepressants 25%
• Endocannabinoids 25%
• Fatty Acid Amide Hydrolase 25%
• After Injection 12%
• High Dose 12%
• Serum Levels 12%
• Male Subjects 12%
• Treatment Strategy 12%
• Pathophysiology 12%
• Genetic Animal Models 12%
• Endocannabinoid System 12%
• Anti-depression 12%
• Related Disorders 12%
• Animal Model Study 12%
• Receptor Antagonist 12%
• Male Rats 12%
• Acute Effects 12%
• Mediating Mechanism 12%
• Oral Ingestion 12%
• AM251 12%

Neuroscience

• Cannabidiol 100%
• Methyl Ester 100%
• Cannabinoid 2 Receptor 100%
• Major Depressive Disorder 25%
• Antidepressant 25%
• Brain-Derived Neurotrophic Factor 25%
• Endocannabinoid 25%
• Fatty Acid Amidase 25%
• Endocannabinoid System 12%
• Receptor Antagonist 12%