Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum

Mayeul Collot; Rémy Kreder; Anatoliy L. Tatarets; Leonid D. Patsenker; Yves Mely; Andrey S. Klymchenko

doi:10.1039/c5cc06094j

Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum

Mayeul Collot
, Rémy Kreder
, Anatoliy L. Tatarets
, Leonid D. Patsenker
, Yves Mely
, Andrey S. Klymchenko

פרסום מחקרי: פרסום בכתב עת › מאמר › ביקורת עמיתים

91 ציטוטים ‏(Scopus)

תקציר

A rational design of squaraine dyes with lipophilic and zwitterionic groups tunes cell entry, allowing for selective far-red/near-infrared imaging of plasma membrane vs. endoplasmic reticulum. They exhibit up to 110-fold fluorescence enhancement in biomembranes and enable cellular imaging at 1 nM concentration, which make them the brightest membrane probes to date.

שפה מקורית	אנגלית
עמודים (מ-עד)	17136-17139
מספר עמודים	4
כתב עת	Chemical Communications
כרך	51
מספר גיליון	96
מזהי עצם דיגיטלי (DOIs)	https://doi.org/10.1039/c5cc06094j
סטטוס פרסום	פורסם - 2015
פורסם באופן חיצוני	כן

גישה למסמך

10.1039/c5cc06094j

קבצים וקישורים אחרים

Link to publication in Scopus

פורמט ציטוט ביבליוגרפי

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title = "Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum",

abstract = "A rational design of squaraine dyes with lipophilic and zwitterionic groups tunes cell entry, allowing for selective far-red/near-infrared imaging of plasma membrane vs. endoplasmic reticulum. They exhibit up to 110-fold fluorescence enhancement in biomembranes and enable cellular imaging at 1 nM concentration, which make them the brightest membrane probes to date.",

author = "Mayeul Collot and R{\'e}my Kreder and Tatarets, \{Anatoliy L.\} and Patsenker, \{Leonid D.\} and Yves Mely and Klymchenko, \{Andrey S.\}",

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year = "2015",

doi = "10.1039/c5cc06094j",

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T1 - Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum

AU - Collot, Mayeul

AU - Kreder, Rémy

AU - Tatarets, Anatoliy L.

AU - Patsenker, Leonid D.

AU - Mely, Yves

AU - Klymchenko, Andrey S.

PY - 2015

Y1 - 2015

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AB - A rational design of squaraine dyes with lipophilic and zwitterionic groups tunes cell entry, allowing for selective far-red/near-infrared imaging of plasma membrane vs. endoplasmic reticulum. They exhibit up to 110-fold fluorescence enhancement in biomembranes and enable cellular imaging at 1 nM concentration, which make them the brightest membrane probes to date.

UR - https://www.scopus.com/pages/publications/84947967214

U2 - 10.1039/c5cc06094j

DO - 10.1039/c5cc06094j

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AN - SCOPUS:84947967214

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VL - 51

SP - 17136

EP - 17139

JO - Chemical Communications

JF - Chemical Communications

IS - 96

ER -

Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum

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