An automated bedside method for measuring functional residual capacity by N2 washout in mechanically ventilated children

Yakov Sivan, Timothy W. Deakers, Christopher J.L. Newth

פרסום מחקרי: פרסום בכתב עתמאמרביקורת עמיתים

40 ציטוטים ‏(Scopus)

תקציר

Beside measurement of functional residual capacity (FRC) in ventilated children is impractical. Using a simple technique based on open circuit N2 washout, we measured FRC in ventilated children. The system was evaluated in the laboratory and in patients. Using a mechanical lung, the reproducibility of 200 studies over a range of 100-500 mL at each of four different flow rates (10 determinations at each level) was very high with a mean coefficient of variation of 2.3% (range 0.5-5.1%). Linearity of the integrated N2 signal for volumes of 100500 mL washed out at different flow rates was excellent (range 7.4-17.9 L/min), r = 0.99. The mean difference between measured and preset mechanical lung volumes was 2.4% (range 0-4.6%). In vivo, reproducibility of six to 10 FRC determinations in each of 30 children gave a mean coefficient of variation of 2.7%. Comparison to the conventional Douglas bag collection method showed a high correlation (r = 0.97). We conclude that this is an easy, highly reproducible, and accurate method for FRC determination suitable to ventilated infants and children.

שפה מקוריתאנגלית
עמודים (מ-עד)446-450
מספר עמודים5
כתב עתPediatric Research
כרך28
מספר גיליון5
מזהי עצם דיגיטלי (DOIs)
סטטוס פרסוםפורסם - נוב׳ 1990
פורסם באופן חיצוניכן

טביעת אצבע

להלן מוצגים תחומי המחקר של הפרסום 'An automated bedside method for measuring functional residual capacity by N2 washout in mechanically ventilated children'. יחד הם יוצרים טביעת אצבע ייחודית.

פורמט ציטוט ביבליוגרפי