TY - JOUR
T1 - A pilot study on the effects of treatment with acamprosate on craving for alcohol in alcohol-dependent patients
AU - Weinstein, Aviv
AU - Feldtkeller, Barbara
AU - Feeney, Adrian
AU - Lingford-Hughes, Anne
AU - Nutt, David J.
PY - 2003/6
Y1 - 2003/6
N2 - This study investigated the effects of treatment with acamprosate on craving for alcohol by using a contextual priming task with alcohol and neutral words and craving questionnaires (ACQ, OCDS) in alcohol-dependent patients who abstained from alcohol for 6 weeks. The acamprosate-treated group (n = 16) were given 666 mg t.d.s. with standard group-work aimed at abstinence. The unmedicated control group (n = 13) received only standard group therapy. The results showed that the acamprosate treated group was faster in their responses to craving-related stimuli and scored lower on craving questionnaires during week 6 compared with week 2. Our results suggest that acamprosate may play a role in reduction of craving for alcohol after 6 weeks of treatment.
AB - This study investigated the effects of treatment with acamprosate on craving for alcohol by using a contextual priming task with alcohol and neutral words and craving questionnaires (ACQ, OCDS) in alcohol-dependent patients who abstained from alcohol for 6 weeks. The acamprosate-treated group (n = 16) were given 666 mg t.d.s. with standard group-work aimed at abstinence. The unmedicated control group (n = 13) received only standard group therapy. The results showed that the acamprosate treated group was faster in their responses to craving-related stimuli and scored lower on craving questionnaires during week 6 compared with week 2. Our results suggest that acamprosate may play a role in reduction of craving for alcohol after 6 weeks of treatment.
UR - http://www.scopus.com/inward/record.url?scp=0037810379&partnerID=8YFLogxK
U2 - 10.1080/1355621031000117464
DO - 10.1080/1355621031000117464
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C2 - 12850782
AN - SCOPUS:0037810379
SN - 1355-6215
VL - 8
SP - 229
EP - 232
JO - Addiction Biology
JF - Addiction Biology
IS - 2
ER -