TY - JOUR
T1 - β-Hydroxy-β-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men
AU - Stout, Jeffrey R.
AU - Fukuda, David H.
AU - Kendall, Kristina L.
AU - Smith-Ryan, Abbie E.
AU - Moon, Jordan R.
AU - Hoffman, Jay R.
N1 - Publisher Copyright:
© 2015.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - The effects of 12-weeks of HMB ingestion and resistance training (RT) on abdominal adiposity were examined in 48 men (66-78. yrs). All participants were randomly assigned to 1 of 4 groups: no-training placebo (NT-PL), HMB only (NT-HMB), RT with PL (RT-PL), or HMB with RT (RT-HMB). DXA was used to estimate abdominal fat mass (AFM) by placing the region of interest over the L1-L4 region of the spine. Outcomes were assessed by ANCOVA, with Bonferroni-corrected pairwise comparisons. Baseline AFM values were used as the covariate. The ANCOVA indicated a significant difference (p. =. 0.013) between group means for the adjusted posttest AFM values (mean (kg). ±. SE: NT-PL. =. 2.59. ±. 0.06; NT-HMB. =. 2.59. ±. 0.61; RT-PL. =. 2.59. ±. 0.62; RT-HMB. =. 2.34. ±. 0.61). The pairwise comparisons indicated that AFM following the intervention period in the RT-HMB group was significantly less than NT-PL (p. =. 0.013), NT-HMB (p. =. 0.011), and RT-PL (p. =. 0.010). These data suggested that HMB in combination with 12. weeks of RT decreased AFM in elderly men.
AB - The effects of 12-weeks of HMB ingestion and resistance training (RT) on abdominal adiposity were examined in 48 men (66-78. yrs). All participants were randomly assigned to 1 of 4 groups: no-training placebo (NT-PL), HMB only (NT-HMB), RT with PL (RT-PL), or HMB with RT (RT-HMB). DXA was used to estimate abdominal fat mass (AFM) by placing the region of interest over the L1-L4 region of the spine. Outcomes were assessed by ANCOVA, with Bonferroni-corrected pairwise comparisons. Baseline AFM values were used as the covariate. The ANCOVA indicated a significant difference (p. =. 0.013) between group means for the adjusted posttest AFM values (mean (kg). ±. SE: NT-PL. =. 2.59. ±. 0.06; NT-HMB. =. 2.59. ±. 0.61; RT-PL. =. 2.59. ±. 0.62; RT-HMB. =. 2.34. ±. 0.61). The pairwise comparisons indicated that AFM following the intervention period in the RT-HMB group was significantly less than NT-PL (p. =. 0.013), NT-HMB (p. =. 0.011), and RT-PL (p. =. 0.010). These data suggested that HMB in combination with 12. weeks of RT decreased AFM in elderly men.
KW - Abdominal fat mass
KW - Aging
KW - Exercise
KW - β-Hydroxy-β-methylbutyrate
UR - http://www.scopus.com/inward/record.url?scp=84923039027&partnerID=8YFLogxK
U2 - 10.1016/j.exger.2015.02.012
DO - 10.1016/j.exger.2015.02.012
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C2 - 25700845
AN - SCOPUS:84923039027
SN - 0531-5565
VL - 64
SP - 33
EP - 34
JO - Experimental Gerontology
JF - Experimental Gerontology
ER -