Use of proton pump inhibitors during pregnancy and breastfeeding

Alejandro A. Nava-Ocampo, Elvia Y. Velázquez-Armenta, Jung Yeol Han, Gideon Koren

Research output: Contribution to journalShort surveypeer-review

17 Scopus citations

Abstract

QUESTION: A 36-year-old pregnant patient has symptoms of peptic disease. Treatment with diet and lifestyle modifications and also antacids has given her little relief. If she were not pregnant, I would prescribe a proton pump inhibitor (PPI) for her. She is now 4 weeks pregnant, and I need to determine whether PPIs are safe during pregnancy. ANSWER: Data currently available suggest that omeprazole is not teratogenic in humans. While information on other PPIs is limited, a systematic review of the evidence suggests that they are also not teratogenic.

Original languageEnglish
Pages (from-to)853-854
Number of pages2
JournalCanadian Family Physician
Volume52
Issue number7
StatePublished - Jul 2006
Externally publishedYes

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