Towards identifying a characteristic neuropsychological profile for fetal alcohol spectrum disorders 1. analysis of the Motherisk FASD clinic

Kelly Nash, Sara Stevens, Joanne Rovet, Ellen Fantus, Irena Nulman, Donna Sorbara, Gideon Koren

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Objective Children with FASD display a heterogeneous profile and may have deficits in physical, behavioural, emotional, and social functioning, as the result of prenatal alcohol exposure. The major objective of the current study was to identify if a specific pattern of neuropsychological functioning exists among children prenatally exposed to alcohol who received a diagnosis, versus exposed children who did not. We compared groups on domains of intellectual functioning, memory, attention, executive functioning, motor functioning, language/communication and achievement. Methods One hundred and seventy children who were seen in the clinic between 2005 and 2009 were included in this study. Out of the total 170 children seen, 109 received an FASD diagnosis. Results We identified a specific neuropsychological profile that typifies children diagnosed with an FASD versus those exposed prenatally to alcohol, who did not receive a diagnosis. Diagnosed children displayed a neuropsychological profile characterized by weaknesses in the areas of verbal reasoning, memory, overall language functioning, math reasoning and calculation. Groups did not differ on measures of attention or executive functioning. Conclusion The information gained from these analyses, are essential for informing best practices for diagnosis and treatment.

Original languageEnglish
Pages (from-to)e44-e52
JournalJournal of Population Therapeutics and Clinical Pharmacology
Volume20
Issue number1
StatePublished - 2013
Externally publishedYes

Keywords

  • Diagnosis
  • Fetal alcohol spectrum disorder
  • Neuropsychological profile

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