Tibial hemimelia and tetralogy of fallot associated with first trimester exposure to amantadine

Paresh B. Pandit; David Chitayat; Ann L. Jefferies; Allison Landes; Izhar U. Qamar; Gideon Koren

doi:10.1016/0890-6238(94)90072-8

Tibial hemimelia and tetralogy of fallot associated with first trimester exposure to amantadine

Paresh B. Pandit
, David Chitayat
, Ann L. Jefferies
, Allison Landes
, Izhar U. Qamar
, Gideon Koren

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Although amantadine hydrochloride has been extensively used for the prevention of influenza A2, few data exist regarding its safety in pregnancy. We report the outcome of a pregnancy during which the mother was treated with amantadine in the first trimester. The infant, born at 29 weeks gestation, has tetralogy of Fallot and tibial hemimelia. Follow-up of the four prospective cases known to date to the Motherisk Program in Toronto did not identify any abnormalities.

Original language	English
Pages (from-to)	89-92
Number of pages	4
Journal	Reproductive Toxicology
Volume	8
Issue number	1
DOIs	https://doi.org/10.1016/0890-6238(94)90072-8
State	Published - 1994
Externally published	Yes

Keywords

amantadine
parainfluenza
pregnancy
tetralogy of Fallot
tetratogens
tibial hemimelia

Access to Document

10.1016/0890-6238(94)90072-8

Cite this

@article{08a3a886214049daac7bac95665c6e96,

title = "Tibial hemimelia and tetralogy of fallot associated with first trimester exposure to amantadine",

abstract = "Although amantadine hydrochloride has been extensively used for the prevention of influenza A2, few data exist regarding its safety in pregnancy. We report the outcome of a pregnancy during which the mother was treated with amantadine in the first trimester. The infant, born at 29 weeks gestation, has tetralogy of Fallot and tibial hemimelia. Follow-up of the four prospective cases known to date to the Motherisk Program in Toronto did not identify any abnormalities.",

keywords = "amantadine, parainfluenza, pregnancy, tetralogy of Fallot, tetratogens, tibial hemimelia",

author = "Pandit, \{Paresh B.\} and David Chitayat and Jefferies, \{Ann L.\} and Allison Landes and Qamar, \{Izhar U.\} and Gideon Koren",

year = "1994",

doi = "10.1016/0890-6238(94)90072-8",

language = "אנגלית",

volume = "8",

pages = "89--92",

journal = "Reproductive Toxicology",

issn = "0890-6238",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Tibial hemimelia and tetralogy of fallot associated with first trimester exposure to amantadine

AU - Pandit, Paresh B.

AU - Chitayat, David

AU - Jefferies, Ann L.

AU - Landes, Allison

AU - Qamar, Izhar U.

AU - Koren, Gideon

PY - 1994

Y1 - 1994

N2 - Although amantadine hydrochloride has been extensively used for the prevention of influenza A2, few data exist regarding its safety in pregnancy. We report the outcome of a pregnancy during which the mother was treated with amantadine in the first trimester. The infant, born at 29 weeks gestation, has tetralogy of Fallot and tibial hemimelia. Follow-up of the four prospective cases known to date to the Motherisk Program in Toronto did not identify any abnormalities.

AB - Although amantadine hydrochloride has been extensively used for the prevention of influenza A2, few data exist regarding its safety in pregnancy. We report the outcome of a pregnancy during which the mother was treated with amantadine in the first trimester. The infant, born at 29 weeks gestation, has tetralogy of Fallot and tibial hemimelia. Follow-up of the four prospective cases known to date to the Motherisk Program in Toronto did not identify any abnormalities.

KW - amantadine

KW - parainfluenza

KW - pregnancy

KW - tetralogy of Fallot

KW - tetratogens

KW - tibial hemimelia

UR - https://www.scopus.com/pages/publications/0028186427

U2 - 10.1016/0890-6238(94)90072-8

DO - 10.1016/0890-6238(94)90072-8

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 8186630

AN - SCOPUS:0028186427

SN - 0890-6238

VL - 8

SP - 89

EP - 92

JO - Reproductive Toxicology

JF - Reproductive Toxicology

IS - 1

ER -

Tibial hemimelia and tetralogy of fallot associated with first trimester exposure to amantadine

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this