TY - JOUR
T1 - The need for liver transplantation
T2 - a nationwide estimate based on consensus review
AU - Modan, B.
AU - Shpilberg, O.
AU - Anis, E.
AU - Chetrit, A.
AU - Luxenburg, O.
AU - Rosenberg, E.
AU - Rosenthol, N.
AU - Sadetski, S.
AU - Benaim, H.
AU - Eckstein, H.
AU - Baruch, Y.
AU - Sikuler, E.
AU - Ashur, Y.
AU - Shouval, D.
PY - 1995/9/9
Y1 - 1995/9/9
N2 - Summary. Orthotopic liver transplantation (OLT) is widely practised in developed countries. The procedure is costly, the supply of donor organs limited, and it is not known how many patients need transplantation. A community-wide estimate of the needs for OLT was performed over two years in all general hospitals in Israel. Records of 1851 patients with liver disease were screened to identify those who might eventually need OLT. The annual estimate of transplantation needs in the country was 10-15·5 per million population, with equal numbers of males and females. The addition of patients with non-reformed alcoholism and end-stage liver disease, originally set as an exclusion criteria, would have added 20% to this estimate. 37% of potential candidates were under 40 years of age at diagnosis, and about 50% were 55-64 years old. Almost 80% of patients had cirrhosis of the liver and 13·6% had fulminant hepatitis. These findings provide a basis for a national plan of OLT in Israel, and similar studies might be useful in other countries.
AB - Summary. Orthotopic liver transplantation (OLT) is widely practised in developed countries. The procedure is costly, the supply of donor organs limited, and it is not known how many patients need transplantation. A community-wide estimate of the needs for OLT was performed over two years in all general hospitals in Israel. Records of 1851 patients with liver disease were screened to identify those who might eventually need OLT. The annual estimate of transplantation needs in the country was 10-15·5 per million population, with equal numbers of males and females. The addition of patients with non-reformed alcoholism and end-stage liver disease, originally set as an exclusion criteria, would have added 20% to this estimate. 37% of potential candidates were under 40 years of age at diagnosis, and about 50% were 55-64 years old. Almost 80% of patients had cirrhosis of the liver and 13·6% had fulminant hepatitis. These findings provide a basis for a national plan of OLT in Israel, and similar studies might be useful in other countries.
UR - http://www.scopus.com/inward/record.url?scp=0029100572&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(95)92279-2
DO - 10.1016/S0140-6736(95)92279-2
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 7658818
AN - SCOPUS:0029100572
SN - 0140-6736
VL - 346
SP - 660
EP - 662
JO - The Lancet
JF - The Lancet
IS - 8976
ER -