Severe Coxsackie virus B infection in preterm newborns treated with pleconaril

Sofia Bauer; Giora Gottesman; Lea Sirota; Ita Litmanovitz; Shay Ashkenazi; Itzhak Levi

doi:10.1007/s00431-002-0929-5

Severe Coxsackie virus B infection in preterm newborns treated with pleconaril

Sofia Bauer, Giora Gottesman, Lea Sirota, Ita Litmanovitz, Shay Ashkenazi, Itzhak Levi

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

Four preterm newborn infants with severe multisystem Coxsackie virus B infection were treated with an oral suspension of pleconaril (5 mg/kg per day). The patients had myocarditis, fulminant hepatitis, meningoencephalitis and disseminated intravascular coagulopathy. All four infants recovered, and no adverse effects of the treatment were noted. Conclusion: pleconaril needs to be comprehensively evaluated in this population.

Original language	English
Pages (from-to)	491-493
Number of pages	3
Journal	European Journal of Pediatrics
Volume	161
Issue number	9
DOIs	https://doi.org/10.1007/s00431-002-0929-5
State	Published - 2002
Externally published	Yes

Keywords

Coxsackie virus
Enterovirus
Neonate
Pleconaril

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10.1007/s00431-002-0929-5

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abstract = "Four preterm newborn infants with severe multisystem Coxsackie virus B infection were treated with an oral suspension of pleconaril (5 mg/kg per day). The patients had myocarditis, fulminant hepatitis, meningoencephalitis and disseminated intravascular coagulopathy. All four infants recovered, and no adverse effects of the treatment were noted. Conclusion: pleconaril needs to be comprehensively evaluated in this population.",

keywords = "Coxsackie virus, Enterovirus, Neonate, Pleconaril",

author = "Sofia Bauer and Giora Gottesman and Lea Sirota and Ita Litmanovitz and Shay Ashkenazi and Itzhak Levi",

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AU - Bauer, Sofia

AU - Gottesman, Giora

AU - Sirota, Lea

AU - Litmanovitz, Ita

AU - Ashkenazi, Shay

AU - Levi, Itzhak

PY - 2002

Y1 - 2002

N2 - Four preterm newborn infants with severe multisystem Coxsackie virus B infection were treated with an oral suspension of pleconaril (5 mg/kg per day). The patients had myocarditis, fulminant hepatitis, meningoencephalitis and disseminated intravascular coagulopathy. All four infants recovered, and no adverse effects of the treatment were noted. Conclusion: pleconaril needs to be comprehensively evaluated in this population.

AB - Four preterm newborn infants with severe multisystem Coxsackie virus B infection were treated with an oral suspension of pleconaril (5 mg/kg per day). The patients had myocarditis, fulminant hepatitis, meningoencephalitis and disseminated intravascular coagulopathy. All four infants recovered, and no adverse effects of the treatment were noted. Conclusion: pleconaril needs to be comprehensively evaluated in this population.

KW - Coxsackie virus

KW - Enterovirus

KW - Neonate

KW - Pleconaril

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ER -

Severe Coxsackie virus B infection in preterm newborns treated with pleconaril

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Keywords

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