Severe Coxsackie virus B infection in preterm newborns treated with pleconaril

Sofia Bauer, Giora Gottesman, Lea Sirota, Ita Litmanovitz, Shay Ashkenazi, Itzhak Levi

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

Four preterm newborn infants with severe multisystem Coxsackie virus B infection were treated with an oral suspension of pleconaril (5 mg/kg per day). The patients had myocarditis, fulminant hepatitis, meningoencephalitis and disseminated intravascular coagulopathy. All four infants recovered, and no adverse effects of the treatment were noted. Conclusion: pleconaril needs to be comprehensively evaluated in this population.

Original languageEnglish
Pages (from-to)491-493
Number of pages3
JournalEuropean Journal of Pediatrics
Volume161
Issue number9
DOIs
StatePublished - 2002
Externally publishedYes

Keywords

  • Coxsackie virus
  • Enterovirus
  • Neonate
  • Pleconaril

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