Safety of lidocaine-prilocaine cream in the treatment of preterm neonates

Anna Taddio, Andrew T. Shennan, Bonnie Stevens, J. Steven Leeder, Gideon Koren

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

The safety of lidocaine-prilocaine cream (EMLA) was evaluated in an open trial in 30 preterm neonates (mean gestational age, 32.8 weeks; birth weight, 1911 gm); 0.5 gm was applied to the heel for 1 hour. Mean baseline and follow-up (4, 8, or 12 hours after EMLA application) methemoglobin levels were not different, ranging from 1.15% to 1.45%, and from 1.13% to 1.49%, respectively. (J PEDIATR 1995;127:1002-5).

Original languageEnglish
Pages (from-to)1002-1005
Number of pages4
JournalJournal of Pediatrics
Volume127
Issue number6
DOIs
StatePublished - Dec 1995

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