Safe use of valproic acid during pregnancy

G. Koren, D. Kennedy

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations

Abstract

QUESTION: I have an epileptic patient who plans pregnancy. It took us years to control her seizures, and valproic acid seems to be the only way to control them. What is the risk to her fetus? ANSWER: Neural tube defects (NTDs) are the most common of the major anomalies associated with in utero exposure to valproic acid. About 1% to 2% of exposed fetuses suffer adverse effects.

Original languageEnglish
Pages (from-to)1451
Number of pages1
JournalCanadian Family Physician
Volume45
Issue numberJUN.
StatePublished - 1999
Externally publishedYes

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