TY - JOUR
T1 - Rifampin augments cytokine-induced nitric oxide production in human alveolar epithelial cells
AU - Yuhas, Yael
AU - Berent, Eva
AU - Ovadiah, Hila
AU - Azoulay, Inbar
AU - Ashkenazi, Shai
PY - 2006/1
Y1 - 2006/1
N2 - Rifampin increased nitric oxide production and inducible nitric oxide synthase expression in alveolar cells stimulated with cytokines. Nitric oxide concentrations after induction with cytokines, cytokines with 10 μg/ml rifampin, and cytokines with 50 μg/ml rifampin were 3.2, 4.5, and 8.8 μM, respectively (P < 0.02 versus cytokines alone). This indicates that rifampin modulates the immune response.
AB - Rifampin increased nitric oxide production and inducible nitric oxide synthase expression in alveolar cells stimulated with cytokines. Nitric oxide concentrations after induction with cytokines, cytokines with 10 μg/ml rifampin, and cytokines with 50 μg/ml rifampin were 3.2, 4.5, and 8.8 μM, respectively (P < 0.02 versus cytokines alone). This indicates that rifampin modulates the immune response.
UR - http://www.scopus.com/inward/record.url?scp=29944432207&partnerID=8YFLogxK
U2 - 10.1128/AAC.50.1.396-398.2006
DO - 10.1128/AAC.50.1.396-398.2006
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C2 - 16377722
AN - SCOPUS:29944432207
SN - 0066-4804
VL - 50
SP - 396
EP - 398
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 1
ER -