TY - JOUR
T1 - Rhabdomyolysis and Acute Renal Failure Induced by Paraphenylenediamine
AU - Averbukh, Z.
AU - Modai, D.
AU - Leonov, Y.
AU - Weissgarten, J.
AU - Lewinsohn, G.
AU - Fucs, L.
AU - Golik, A.
AU - Rosenmann, E.
PY - 1989/9
Y1 - 1989/9
N2 - 1 We present a 40-year-old healthy man who developed a typical clinical picture of rhabdomyolysis following the administration of paraphenylenediamine by a witchdoctor as a pain killer. 2 Two groups of 15 mice were given paraphenylenediamine 70 mg/kg and 35 mg/kg respectively. Biochemical and histological findings of rhabdomyolysis developed in both groups, without kidney damage. 3 Paraphenylenediamine may cause rhabdomyolysis resulting in acute renal failure in humans. In mice, however, it produces rhabdomyolysis, but the kidneys are not affected.
AB - 1 We present a 40-year-old healthy man who developed a typical clinical picture of rhabdomyolysis following the administration of paraphenylenediamine by a witchdoctor as a pain killer. 2 Two groups of 15 mice were given paraphenylenediamine 70 mg/kg and 35 mg/kg respectively. Biochemical and histological findings of rhabdomyolysis developed in both groups, without kidney damage. 3 Paraphenylenediamine may cause rhabdomyolysis resulting in acute renal failure in humans. In mice, however, it produces rhabdomyolysis, but the kidneys are not affected.
UR - http://www.scopus.com/inward/record.url?scp=84965853640&partnerID=8YFLogxK
U2 - 10.1177/096032718900800502
DO - 10.1177/096032718900800502
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C2 - 2807301
AN - SCOPUS:84965853640
SN - 0960-3271
VL - 8
SP - 345
EP - 348
JO - Human and Experimental Toxicology
JF - Human and Experimental Toxicology
IS - 5
ER -