Rett syndrome and aging

Joav Merrick; Joav Merrick; Meir Lotan; Meir Lotan; Meir Lotan; Mohammed Morad; Mohammed Morad; Isack Kandle

doi:10.1515/IJDHD.2006.5.1.23

Rett syndrome and aging

Joav Merrick, Joav Merrick, Meir Lotan, Meir Lotan, Meir Lotan, Mohammed Morad, Mohammed Morad, Isack Kandle

Department of Physical Therapy

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Rett syndrome (RS) is a neurological disease characterized by an arrest of brain development caused by an X chromosome mutation affecting mainly females. Rett syndrome is the first human disease found to be caused by defects in a protein involved in regulating gene expression through its interaction with methylated DNA. The disease has been traced to a defective gene called MECP2 on the X chromosome. This review of aging with RS revealed very few studies, but the published case stories showed that females with RS can live even to age 79 years, but larger studies are needed to bring more light into the natural and long-term consequences of this syndrome.

Original language	English
Pages (from-to)	23-26
Number of pages	4
Journal	International Journal on Disability and Human Development
Volume	5
Issue number	1
DOIs	https://doi.org/10.1515/IJDHD.2006.5.1.23
State	Published - 2006

Keywords

Aging
Israel
Rett syndrome
long-term care

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10.1515/IJDHD.2006.5.1.23

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Rett syndrome and aging

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Keywords

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