Retinoic Acid Embryopathy

Franz W. Rosa; Gideon Koren; Charles V. Vorhees; Edward J. Lammer

doi:10.1056/NEJM198607243150416

Retinoic Acid Embryopathy

Franz W. Rosa
, Gideon Koren
, Charles V. Vorhees
, Edward J. Lammer

Research output: Contribution to journal › Letter › peer-review

22 Scopus citations

Abstract

To the Editor: Here are several supplementary comments on the excellent report on retinoic acid embryopathy by Lammer et al. (Oct. 3 issue).* Since the time of that compilation of cases (July 1984), 20 additional cases of isotretinoin embryopathy have been reported to the Food and Drug Administration. Fifteen of these patients were born between May 1984 and August 1985, and five earlier cases have come to light since the compilation. With increasing awareness of teratogenicity, a higher proportion of cases of exposure are being reported before birth. Six of 20 cases were recognized antenatally; 5 of the 6 pregnancies…

Original language	English
Pages (from-to)	262-263
Number of pages	2
Journal	New England Journal of Medicine
Volume	315
Issue number	4
DOIs	https://doi.org/10.1056/NEJM198607243150416
State	Published - 24 Jul 1986
Externally published	Yes

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title = "Retinoic Acid Embryopathy",

abstract = "To the Editor: Here are several supplementary comments on the excellent report on retinoic acid embryopathy by Lammer et al. (Oct. 3 issue).* Since the time of that compilation of cases (July 1984), 20 additional cases of isotretinoin embryopathy have been reported to the Food and Drug Administration. Fifteen of these patients were born between May 1984 and August 1985, and five earlier cases have come to light since the compilation. With increasing awareness of teratogenicity, a higher proportion of cases of exposure are being reported before birth. Six of 20 cases were recognized antenatally; 5 of the 6 pregnancies…",

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AU - Rosa, Franz W.

AU - Koren, Gideon

AU - Vorhees, Charles V.

AU - Lammer, Edward J.

PY - 1986/7/24

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N2 - To the Editor: Here are several supplementary comments on the excellent report on retinoic acid embryopathy by Lammer et al. (Oct. 3 issue).* Since the time of that compilation of cases (July 1984), 20 additional cases of isotretinoin embryopathy have been reported to the Food and Drug Administration. Fifteen of these patients were born between May 1984 and August 1985, and five earlier cases have come to light since the compilation. With increasing awareness of teratogenicity, a higher proportion of cases of exposure are being reported before birth. Six of 20 cases were recognized antenatally; 5 of the 6 pregnancies…

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Retinoic Acid Embryopathy

Abstract

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