TY - JOUR
T1 - Retinoic Acid Embryopathy
AU - Rosa, Franz W.
AU - Koren, Gideon
AU - Vorhees, Charles V.
AU - Lammer, Edward J.
PY - 1986/7/24
Y1 - 1986/7/24
N2 - To the Editor: Here are several supplementary comments on the excellent report on retinoic acid embryopathy by Lammer et al. (Oct. 3 issue).* Since the time of that compilation of cases (July 1984), 20 additional cases of isotretinoin embryopathy have been reported to the Food and Drug Administration. Fifteen of these patients were born between May 1984 and August 1985, and five earlier cases have come to light since the compilation. With increasing awareness of teratogenicity, a higher proportion of cases of exposure are being reported before birth. Six of 20 cases were recognized antenatally; 5 of the 6 pregnancies…
AB - To the Editor: Here are several supplementary comments on the excellent report on retinoic acid embryopathy by Lammer et al. (Oct. 3 issue).* Since the time of that compilation of cases (July 1984), 20 additional cases of isotretinoin embryopathy have been reported to the Food and Drug Administration. Fifteen of these patients were born between May 1984 and August 1985, and five earlier cases have come to light since the compilation. With increasing awareness of teratogenicity, a higher proportion of cases of exposure are being reported before birth. Six of 20 cases were recognized antenatally; 5 of the 6 pregnancies…
UR - http://www.scopus.com/inward/record.url?scp=0023039495&partnerID=8YFLogxK
U2 - 10.1056/NEJM198607243150416
DO - 10.1056/NEJM198607243150416
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C2 - 3459962
AN - SCOPUS:0023039495
SN - 0028-4793
VL - 315
SP - 262
EP - 263
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 4
ER -