Reporting bias in retrospective ascertainment of drug-induced embryopathy

Benjamin Bar-Oz; Myla E. Moretti; Guy Mareels; Tony Van Tittelboom; Gideon Koren

doi:10.1016/S0140-6736(99)04411-6

Reporting bias in retrospective ascertainment of drug-induced embryopathy

Benjamin Bar-Oz
, Myla E. Moretti
, Guy Mareels
, Tony Van Tittelboom
, Gideon Koren

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

Original language	English
Pages (from-to)	1700-1701
Number of pages	2
Journal	The Lancet
Volume	354
Issue number	9191
DOIs	https://doi.org/10.1016/S0140-6736(99)04411-6
State	Published - 13 Nov 1999
Externally published	Yes

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10.1016/S0140-6736(99)04411-6

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title = "Reporting bias in retrospective ascertainment of drug-induced embryopathy",

abstract = "The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2\%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.",

author = "Benjamin Bar-Oz and Moretti, \{Myla E.\} and Guy Mareels and \{Van Tittelboom\}, Tony and Gideon Koren",

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AU - Bar-Oz, Benjamin

AU - Moretti, Myla E.

AU - Mareels, Guy

AU - Van Tittelboom, Tony

AU - Koren, Gideon

PY - 1999/11/13

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N2 - The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

AB - The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

UR - https://www.scopus.com/pages/publications/0033552390

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VL - 354

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JO - The Lancet

JF - The Lancet

IS - 9191

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Reporting bias in retrospective ascertainment of drug-induced embryopathy

Abstract

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