Reporting bias in retrospective ascertainment of drug-induced embryopathy

Benjamin Bar-Oz; Myla E. Moretti; Guy Mareels; Tony Van Tittelboom; Gideon Koren

doi:10.1016/S0140-6736(99)04411-6

Reporting bias in retrospective ascertainment of drug-induced embryopathy

Benjamin Bar-Oz, Myla E. Moretti, Guy Mareels, Tony Van Tittelboom, Gideon Koren

Research output: Contribution to journal › Article › peer-review

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Abstract

The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

Original language	English
Pages (from-to)	1700-1701
Number of pages	2
Journal	The Lancet
Volume	354
Issue number	9191
DOIs	https://doi.org/10.1016/S0140-6736(99)04411-6
State	Published - 13 Nov 1999
Externally published	Yes

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10.1016/S0140-6736(99)04411-6

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title = "Reporting bias in retrospective ascertainment of drug-induced embryopathy",

abstract = "The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.",

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AU - Koren, Gideon

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N2 - The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

AB - The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

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Reporting bias in retrospective ascertainment of drug-induced embryopathy

Abstract

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