TY - JOUR
T1 - Pulmonary Valve Stenosis and Hemophilia A
T2 - Report of Three Cases and Discussion of a Possible Genetic Linkage
AU - Ackerman, Zvi
AU - Koren, Gideon
AU - Gotsman, Mervyn
AU - Eldor, Amiram
PY - 1986/11
Y1 - 1986/11
N2 - • We treated three unrelated patients with hemophilia A and congenital pulmonary valve stenosis. In two patients, the occurrence of the cardiac malformation was sporadic and in one familial. The coexistence of hemophilia A and pulmonary valve stenosis might suggest a genetic linkage for both disorders. Review of the literature supports the hypothesis that the inheritance of pulmonary valve stenosis is dominant and X-linked.
AB - • We treated three unrelated patients with hemophilia A and congenital pulmonary valve stenosis. In two patients, the occurrence of the cardiac malformation was sporadic and in one familial. The coexistence of hemophilia A and pulmonary valve stenosis might suggest a genetic linkage for both disorders. Review of the literature supports the hypothesis that the inheritance of pulmonary valve stenosis is dominant and X-linked.
UR - http://www.scopus.com/inward/record.url?scp=0023030756&partnerID=8YFLogxK
U2 - 10.1001/archinte.1986.00360230173024
DO - 10.1001/archinte.1986.00360230173024
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 3778055
AN - SCOPUS:0023030756
SN - 0003-9926
VL - 146
SP - 2233
EP - 2234
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 11
ER -