Protein conservation by the immature intestine

Y. Sivan, G. Dinari, E. Wielunski, H. Marcus, Y. Rosenbach, I. Zahavi, M. Nitzan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Uptake of intact macromolecules by the immature gut is a well-known phenomenon, but no information exists on the possibility that there is also increased protein loss in the intestinal lumen in preterm infants. We determined alpha-1-antitrypsin (A-1-AT) levels in fecal samples from 39 infants born after 27-41 weeks of gestation from birth up to 30 days of age. A-1-AT levels were elevated only in meconial stools, and low in nonmeconial stools, regardless of associated respiratory disorders, drug administration, and type of nutrition. This study shows that the immature graft has a mature pattern of protein conservation at least as early as after 29 weeks of gestation.

Original languageEnglish
Pages (from-to)32-35
Number of pages4
JournalBiology of the Neonate
Issue number1
StatePublished - 1985
Externally publishedYes


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