TY - JOUR
T1 - Prenatal diagnosis and gonadal findings in X/XXX mosaicism
AU - Kohn, G.
AU - Cohen, M. M.
AU - Beyth, Y.
AU - Ornoy, A.
PY - 1977
Y1 - 1977
N2 - Prenatal diagnosis of a case of X/XXX mosaicism is presented. In spite of the fact that over 50% of the cells cultured from both ovaries were trisomic for the X chromosome, fetal oocytes were rarely found. This case illustrates that the presence of a triple-X cell line, even in a relatively high percentage of ovarian cells, does not necessarily protect the ovary from 'aoogenesis'. This observation might prove useful in the counselling of future cases involving the prenatal detection of sex chromosome mosaicism.
AB - Prenatal diagnosis of a case of X/XXX mosaicism is presented. In spite of the fact that over 50% of the cells cultured from both ovaries were trisomic for the X chromosome, fetal oocytes were rarely found. This case illustrates that the presence of a triple-X cell line, even in a relatively high percentage of ovarian cells, does not necessarily protect the ovary from 'aoogenesis'. This observation might prove useful in the counselling of future cases involving the prenatal detection of sex chromosome mosaicism.
UR - http://www.scopus.com/inward/record.url?scp=0017351816&partnerID=8YFLogxK
U2 - 10.1136/jmg.14.2.120
DO - 10.1136/jmg.14.2.120
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C2 - 856232
AN - SCOPUS:0017351816
SN - 0022-2593
VL - 14
SP - 120
EP - 123
JO - Journal of Medical Genetics
JF - Journal of Medical Genetics
IS - 2
ER -