Abstract
Current recommendations state that pregnant women should not receive the rubella vaccine. However, half of pregnancies are unplanned and hence pregnant women do receive this vaccine. Objectives: To assess the rate of major malformations and to compare developmental milestones in the offspring of women who received rubella vaccine 3 month pre or post conception. Patients and Methods: We prospectively collected and followed up women who received rubella vaccination 3 mo pre or post conception. Control group consisted of women who were not exposed to teratogens during pregnancy. Results: 94 follow-ups were completed in each group. Rates of major malformations were similar as were birth weights and developmental milestones. Rate of therapeutic abortions was higher (p<0.05) in the exposed group (7.4% vs 0%). Conclusion: The results of this study provides additional evidence that rubella vaccination in pregnancy does not affect pregnancy outcome rate of malformations and developmental milestones.
| Original language | English |
|---|---|
| Pages (from-to) | P83 |
| Journal | Clinical Pharmacology and Therapeutics |
| Volume | 69 |
| Issue number | 2 |
| State | Published - 2001 |
| Externally published | Yes |