Positive and Negative Effects of Cannabis and Cannabinoids on Health

Koby Cohen, Abraham Weizman, Aviv Weinstein

Research output: Contribution to journalReview articlepeer-review

155 Scopus citations


Cannabis is the most popular illicit drug in the Western world. Repeated cannabis use has been associated with short- and long-term side effects, including respiratory and cardiovascular disorders, cognitive alterations, psychosis, schizophrenia, and mood disorders. However, casual relations between cannabis use and these adverse effects are missing. On the other hand, recent research proposed promising therapeutic potential of cannabinoid-based drugs for a wide range of medical conditions, including neurological and psychiatric disorders. The current article presents a contemporary review on the adverse effects, safety, and the therapeutic potential of cannabis and cannabinoid-based drugs. Given the growing popularity in the use of cannabinoid-based drugs for both recreational and medical purposes and their potential harmful effects, there is a need for further investigation in this field.

Original languageEnglish
Pages (from-to)1139-1147
Number of pages9
JournalClinical Pharmacology and Therapeutics
Issue number5
StatePublished - May 2019


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