TY - JOUR
T1 - Pituitary-adrenal responses to arm versus leg exercise in untrained man
AU - Maresh, Carl M.
AU - Sökmen, Bülent
AU - Kraemer, William J.
AU - Hoffman, Jay R.
AU - Watson, Greig
AU - Judelson, Daniel A.
AU - Gabaree-Boulant, Catherine L.
AU - Deschenes, Michael R.
AU - VanHeest, Jaci L.
AU - Armstrong, Lawrence E.
N1 - Funding Information:
Acknowledgments The authors thank Sharon Dunphy, Cindy Palmer and Cheryl Weseman for their technical assistance, and the subjects for their cooperation. The study was partially supported by a grant from the University of Connecticut Research Foundation.
PY - 2006/7
Y1 - 2006/7
N2 - The purpose of this study was to examine pituitary-adrenal (PA) hormone responses [beta-endorphin (β-END), adrenocorticotropic hormone (ACTH) and cortisol] to arm exercise (AE) and leg exercise (LE) at 60 and 80% of the muscle-group specific VO2 peak. Eight healthy untrained men (AE VO2 peak = 32.4±3.0 ml kg-1 min-1, LE VO2 peak = 46.9±5.3 ml kg-1 min-1) performed two sub-maximal AE and LE tests in random order. Plasma β-END, ACTH and cortisol were not different (P>0.05) between AE and LE at either exercise intensity; the 60% testing elicited no changes from pre-exercise (PRE) values. For 80% testing, plasma β-END, ACTH and cortisol were consistently, but not significantly, greater during LE than AE. In general, plasma β-END and ACTH were higher (P<0.05) during 80% exercise, than PRE, for both AE and LE. Plasma cortisol was elevated (P<0.05) above PRE during 80% LE, and following 80% for both AE and LE. Plasma ACTH was higher (P<0.05) during 80% LE and AE versus 60% LE and AE, respectively. Plasma β-END and cortisol were significantly higher during and immediately after 80% LE than 60% LE. Thus, plasma β-END, ACTH and cortisol responses were similar for AE and LE at the two relative exercise intensities, with the intensity threshold occurring somewhere between 60 and 80% of VO2 peak. It appears that the smaller muscle mass associated with AE was sufficient to stimulate these PA axis hormones in a manner similar to LE, despite the higher metabolic stress (i.e., plasma La-) associated with LE.
AB - The purpose of this study was to examine pituitary-adrenal (PA) hormone responses [beta-endorphin (β-END), adrenocorticotropic hormone (ACTH) and cortisol] to arm exercise (AE) and leg exercise (LE) at 60 and 80% of the muscle-group specific VO2 peak. Eight healthy untrained men (AE VO2 peak = 32.4±3.0 ml kg-1 min-1, LE VO2 peak = 46.9±5.3 ml kg-1 min-1) performed two sub-maximal AE and LE tests in random order. Plasma β-END, ACTH and cortisol were not different (P>0.05) between AE and LE at either exercise intensity; the 60% testing elicited no changes from pre-exercise (PRE) values. For 80% testing, plasma β-END, ACTH and cortisol were consistently, but not significantly, greater during LE than AE. In general, plasma β-END and ACTH were higher (P<0.05) during 80% exercise, than PRE, for both AE and LE. Plasma cortisol was elevated (P<0.05) above PRE during 80% LE, and following 80% for both AE and LE. Plasma ACTH was higher (P<0.05) during 80% LE and AE versus 60% LE and AE, respectively. Plasma β-END and cortisol were significantly higher during and immediately after 80% LE than 60% LE. Thus, plasma β-END, ACTH and cortisol responses were similar for AE and LE at the two relative exercise intensities, with the intensity threshold occurring somewhere between 60 and 80% of VO2 peak. It appears that the smaller muscle mass associated with AE was sufficient to stimulate these PA axis hormones in a manner similar to LE, despite the higher metabolic stress (i.e., plasma La-) associated with LE.
KW - Adrenocorticotropic hormone
KW - Beta-endorphin
KW - Cortisol
KW - Muscle-group specific VOpeak
UR - http://www.scopus.com/inward/record.url?scp=33745445354&partnerID=8YFLogxK
U2 - 10.1007/s00421-006-0198-5
DO - 10.1007/s00421-006-0198-5
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C2 - 16685546
AN - SCOPUS:33745445354
SN - 1439-6319
VL - 97
SP - 471
EP - 477
JO - European Journal of Applied Physiology
JF - European Journal of Applied Physiology
IS - 4
ER -