Pharmacokinetics of fentanyl in children with renal disease

G. Koren, P. Crean, G. V. Goresky, J. Klein, S. M. MacLeod

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Two cases of fentanyl anesthesia in children with renal diseases are described. In a case of end stage renal failure, the pharmacokinetic parameters during cardiac surgery were similar to 18 children from the same age group with normal renal function. In a case of Wilm's tumor, there was an unusually prolonged elimination half-life of fentanyl and smaller distribution volume as compared to pediatric parameters during fentanyl anesthesia.

Original languageEnglish
Pages (from-to)371-379
Number of pages9
JournalResearch Communications in Chemical Pathology and Pharmacology
Issue number3
StatePublished - 1984
Externally publishedYes


Dive into the research topics of 'Pharmacokinetics of fentanyl in children with renal disease'. Together they form a unique fingerprint.

Cite this