TY - JOUR
T1 - Penta-glycine copper(II) complexes in slightly alkaline solutions
AU - Gaisin, Zeev
AU - Gellerman, Gary
AU - Meyerstein, Dan
N1 - Publisher Copyright:
© 2016 Elsevier Ltd. All rights reserved.
PY - 2016/8/24
Y1 - 2016/8/24
N2 - The kinetics of the reaction of CuII(GGG), CuII(GGGGG) and CuII(GGGGS), where G = glycine and S = sarcosine, with 4-nitrophenyl-acetate were measured. The results point out that at pH 9.0 hydroxide is an axial, or equatorial ligand to a significant amount of these complexes. The source of the different mechanisms of reaction of the analogous nickel complexes is attributed to the axial water ligand of the copper complexes. The biological implications of axial hydroxide binding to copper peptides is discussed.
AB - The kinetics of the reaction of CuII(GGG), CuII(GGGGG) and CuII(GGGGS), where G = glycine and S = sarcosine, with 4-nitrophenyl-acetate were measured. The results point out that at pH 9.0 hydroxide is an axial, or equatorial ligand to a significant amount of these complexes. The source of the different mechanisms of reaction of the analogous nickel complexes is attributed to the axial water ligand of the copper complexes. The biological implications of axial hydroxide binding to copper peptides is discussed.
KW - Copper peptide structures
KW - Hydroxide as an axial ligand
KW - Kinetics
KW - Penta-coordinated copper
UR - http://www.scopus.com/inward/record.url?scp=84974633269&partnerID=8YFLogxK
U2 - 10.1016/j.ica.2016.05.055
DO - 10.1016/j.ica.2016.05.055
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AN - SCOPUS:84974633269
SN - 0020-1693
VL - 450
SP - 211
EP - 215
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
ER -