Outcome of oncology patients in the pediatric intensive care unit

Y. Sivan; P. H. Schwartz; T. Schonfeld; I. J. Cohen; C. J.L. Newth

doi:10.1007/BF01708402

Outcome of oncology patients in the pediatric intensive care unit

Y. Sivan, P. H. Schwartz, T. Schonfeld, I. J. Cohen, C. J.L. Newth

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Abstract

We evaluated the outcome of oncology patients in the Pediatric Intensive Care Unit (PICU) from a total of 72 consecutive admissions. Severity of illness and quantity of care were measured by the Physiologic Stability Index (PSI) and the Therapeutic Intervention Scoring System (TISS), respectively. The overall mortality was 51% and was especially high in patients admitted for acute organ system failure (OSF)-66%. Acute respiratory failure was the most frequent OSF (73%) and the most common cause for PICU admission. A poor outcome was associated with severe leucopenia (<1000 WBC/mm³, 91% mortality), acute renal failure (94% mortality) and central nervous system deterioration (83% mortality). When the outcome was predicted using a quantitative algorithm the observed mortality was significantly higher than the predicted for all admissions with a PSI higher than 5. Improved scoring systems are required to enable characterization of pediatric cancer patients admitted to the PICU.

Original language	English
Pages (from-to)	11-15
Number of pages	5
Journal	Intensive Care Medicine
Volume	17
Issue number	1
DOIs	https://doi.org/10.1007/BF01708402
State	Published - Jan 1991
Externally published	Yes

Keywords

Cancer
Children
Intensive care
Prognosis

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10.1007/BF01708402

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abstract = "We evaluated the outcome of oncology patients in the Pediatric Intensive Care Unit (PICU) from a total of 72 consecutive admissions. Severity of illness and quantity of care were measured by the Physiologic Stability Index (PSI) and the Therapeutic Intervention Scoring System (TISS), respectively. The overall mortality was 51% and was especially high in patients admitted for acute organ system failure (OSF)-66%. Acute respiratory failure was the most frequent OSF (73%) and the most common cause for PICU admission. A poor outcome was associated with severe leucopenia (<1000 WBC/mm3, 91% mortality), acute renal failure (94% mortality) and central nervous system deterioration (83% mortality). When the outcome was predicted using a quantitative algorithm the observed mortality was significantly higher than the predicted for all admissions with a PSI higher than 5. Improved scoring systems are required to enable characterization of pediatric cancer patients admitted to the PICU.",

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AU - Schwartz, P. H.

AU - Schonfeld, T.

AU - Cohen, I. J.

AU - Newth, C. J.L.

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Outcome of oncology patients in the pediatric intensive care unit

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Keywords

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