Numerical analysis of Venous External Scaffolding Technology for Saphenous Vein Grafts

T. Meirson, E. Orion, I. Avrahami

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

This paper presents a method for analyzing and comparing numerically Saphenous Vein Grafts (SVGs) following Coronary Artery Bypass Graft surgery (CABG). The method analyses the flow dynamics inside vein grafts with and without supporting using Venous External Scaffolding Technology (VEST). The numerical method uses patients' specific computational fluid dynamics (CFD) methods to characterize the relevant hemodynamic parameters of patients' SVGs. The method was used to compare the hemodynamics of six patient's specific model and flow conditions of stented and non-stented SVGs, 12 months post-transplantation. The flow parameters used to characterize the grafts' hemodynamics include Time Averaged Wall Shear Stress (TAWSS), Oscillatory Shear Index (OSI) and Relative Residence Time (RRT). The effect of stenting was clearly demonstrated by the chosen parameters. SVGs under constriction of VEST were associated with similar spatial average of TAWSS (10.73 vs 10.29 dyn/cm2), yet had fewer lesions with low TAWSS, lower OSI (0.041 vs 0.08) and RRT (0.12 vs 0.24), and more uniform flow with less flow discrepancies. In conclusion, the suggested method and parameters well demonstrated the advantage of VEST support. Stenting vein grafts with VEST improved hemodynamic factors which are correlated to graft failure following CABG procedure.

Original languageEnglish
Pages (from-to)2090-2095
Number of pages6
JournalJournal of Biomechanics
Volume48
Issue number10
DOIs
StatePublished - 16 Jul 2015

Keywords

  • CABG
  • CFD
  • Hemodynamics
  • Saphenous vein
  • VEST

Fingerprint

Dive into the research topics of 'Numerical analysis of Venous External Scaffolding Technology for Saphenous Vein Grafts'. Together they form a unique fingerprint.

Cite this