Novel approaches to the diagnosis of fetal alcohol spectrum disorder

Daniela L. Caprara; Kelly Nash; Rachel Greenbaum; Joanne Rovet; Gideon Koren

doi:10.1016/j.neubiorev.2006.06.015

Novel approaches to the diagnosis of fetal alcohol spectrum disorder

Daniela L. Caprara
, Kelly Nash
, Rachel Greenbaum
, Joanne Rovet
, Gideon Koren

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

The diagnosis of fetal alcohol spectrum disorder is a difficult task, especially in cases where clear, physical markers of in utero alcohol exposure are not apparent. Reviewed in the following paper are some older tools for screening alcohol use in pregnancy and present novel approaches to the diagnosis of FASD, including ethanol biomarker development to behavioural phenotyping. Improving current FASD diagnostic methodology through more novel approaches may provide the possibility of earlier and wider diagnosis, allowing intervention and treatment at stages where the advanced effects of alcohol can still be mitigated.

Original language	English
Pages (from-to)	254-260
Number of pages	7
Journal	Neuroscience and Biobehavioral Reviews
Volume	31
Issue number	2
DOIs	https://doi.org/10.1016/j.neubiorev.2006.06.015
State	Published - 2007
Externally published	Yes

Keywords

Behavioral phenotyping
Diagnosis
Fatty acid ethyl esters
Fetal alcohol spectrum disorder
Hair and meconium screening
T-ACE
TWEAK

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10.1016/j.neubiorev.2006.06.015

Cite this

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title = "Novel approaches to the diagnosis of fetal alcohol spectrum disorder",

abstract = "The diagnosis of fetal alcohol spectrum disorder is a difficult task, especially in cases where clear, physical markers of in utero alcohol exposure are not apparent. Reviewed in the following paper are some older tools for screening alcohol use in pregnancy and present novel approaches to the diagnosis of FASD, including ethanol biomarker development to behavioural phenotyping. Improving current FASD diagnostic methodology through more novel approaches may provide the possibility of earlier and wider diagnosis, allowing intervention and treatment at stages where the advanced effects of alcohol can still be mitigated.",

keywords = "Behavioral phenotyping, Diagnosis, Fatty acid ethyl esters, Fetal alcohol spectrum disorder, Hair and meconium screening, T-ACE, TWEAK",

author = "Caprara, \{Daniela L.\} and Kelly Nash and Rachel Greenbaum and Joanne Rovet and Gideon Koren",

note = "Funding Information: Supported by Grants by CIHR (NET Grant and MT 1787). DC was recipient of an open studentship from The University of Toronto. G. Koren is a Senior Scientist of CIHR and holder of the Ivey Chair in Molecular Toxicology, The University of Western Ontario.",

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AU - Nash, Kelly

AU - Greenbaum, Rachel

AU - Rovet, Joanne

AU - Koren, Gideon

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AB - The diagnosis of fetal alcohol spectrum disorder is a difficult task, especially in cases where clear, physical markers of in utero alcohol exposure are not apparent. Reviewed in the following paper are some older tools for screening alcohol use in pregnancy and present novel approaches to the diagnosis of FASD, including ethanol biomarker development to behavioural phenotyping. Improving current FASD diagnostic methodology through more novel approaches may provide the possibility of earlier and wider diagnosis, allowing intervention and treatment at stages where the advanced effects of alcohol can still be mitigated.

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KW - Diagnosis

KW - Fatty acid ethyl esters

KW - Fetal alcohol spectrum disorder

KW - Hair and meconium screening

KW - T-ACE

KW - TWEAK

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ER -

Novel approaches to the diagnosis of fetal alcohol spectrum disorder

Abstract

Keywords

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