Non-ionizing millimeter waves non-thermal radiation of saccharomyces cerevisiae—Insights and interactions

Ayan Barbora, Shailendra Rajput, Konstantin Komoshvili, Jacob Levitan, Asher Yahalom, Stella Liberman-Aronov

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Non-ionizing millimeter-waves (MMW) interact with cells in a variety of ways. Here the inhibited cell division effect was investigated using 85–105 GHz MMW irradiation within the International Commission on Non-Ionizing Radiation Protection (ICNIRP) non-thermal 20 mW/cm2 safety standards. Irradiation using a power density of about 1.0 mW/cm2 SAR over 5–6 h on 50 cells/µL samples of Saccharomyces cerevisiae model organism resulted in 62% growth rate reduction compared to the control (sham). The effect was specific for 85–105 GHz range and was energy-and cell density-dependent. Irradiation of wild type and ∆rad52 (DNA damage repair gene) deleted cells presented no differences of colony growth profiles indicating non-thermal MMW treatment does not cause permanent genetic alterations. Dose versus response relations studied using a standard horn antenna (~1.0 mW/cm2) and compared to that of a compact waveguide (17.17 mW/cm2) for increased power delivery resulted in complete termination of cell division via non-thermal processes supported by temperature rise measurements. We have shown that non-thermal MMW radiation has potential for future use in treatment of yeast related diseases and other targeted biomedical outcomes.

Original languageEnglish
Article number6635
JournalApplied Sciences (Switzerland)
Issue number14
StatePublished - 2 Jul 2021


  • Millimeter waves
  • Non-invasive devices
  • Non-ionizing radiation
  • Novel biomedical applications
  • Yeast


Dive into the research topics of 'Non-ionizing millimeter waves non-thermal radiation of saccharomyces cerevisiae—Insights and interactions'. Together they form a unique fingerprint.

Cite this