New insights about chronic pelvic pain syndrome (CPPS)

Keren Grinberg, Yael Sela, Rachel Nissanholtz-Gannot

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations


Background: Chronic pelvic pain syndrome (CPPS) is one of the common diseases in urology and gynecology. CPPS is a multifactorial disorder where pain may originate in any of the urogynecological, gastrointestinal, pelvic musculoskeletal, or nervous systems. The symptoms of CPPS appear to result from an interplay between psychological factors and dysfunction in the immune, neurological, and endocrine systems. The aim of this article was to present new insight about CPPS in order to raise awareness of nursing and medical staff in the identification and diagnosis of the syndrome and to promote an appropriate treatment for each woman who suffers from CPPS. Methods: A literature review about the factors associated with CPPS and therapeutic interventions for CPPS was conducted. Results: CPPS represents a chronic pain syndrome that combines anatomic malfunction of the pelvic floor muscles with malfunction of pain perception linked with psychological and cognitive factors. Conclusions: The therapeutic interventions in CPPS cases should, consequently, follow a multidisciplinary approach.

Original languageEnglish
Article number3005
JournalInternational Journal of Environmental Research and Public Health
Issue number9
StatePublished - 1 May 2020


  • Chronic pelvic pain syndrome (cpps)
  • Gynecology
  • Musculoskeletal pain
  • Therapeutic interventions
  • Urology


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