Abstract
An 85-year-old woman, with known stable angina pectoris, was prescribed 5-fluorouracil cream to treat a small basal cell carcinoma on the forehead. Half an hour after application the patient developed her typical ischemic pain which persisted for 2 hours. Rechallenge, during hospitalization, resulted in recurrence of symptoms that were effectively controlled with sublingual isosorbide dinitrate. Prophylactic therapy with nitroglycerin patch enabled further use of the 5-fluorouracil cream for the next month.
| Original language | English |
|---|---|
| Pages (from-to) | 282-283 |
| Number of pages | 2 |
| Journal | International Journal of Cardiology |
| Volume | 49 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1995 |
| Externally published | Yes |
Keywords
- 5-fluorouracil
- Cardiotoxicity
- Coronary spasm
- Nitrates