Mutation in West Nile virus structural protein prM during human infection

Yaniv Lustig, Robert S. Lanciotti, Musa Hindiyeh, Nathan Keller, Ron Milo, Shlomo Mayan, Ella Mendelson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient’s urine and serum in the presence of low-level neutralizing antibodies. This case demonstrates active replication of WNV during persistent infection.

Original languageEnglish
Pages (from-to)1647-1649
Number of pages3
JournalEmerging Infectious Diseases
Volume22
Issue number9
DOIs
StatePublished - Sep 2016
Externally publishedYes

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