Multiorgan dysfunction and disseminated intravascular coagulation in children receiving lamotrigine and valproic acid

D. S. Chattergoon, M. A. McGuigan, G. Koren, P. Hwang, Shinya Ito

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Two children developed multiorgan dysfunction with disseminated intravascular coagulation 9 days after lamotrigine was added to their antiepileptic therapy, which included valproic acid. During the episodes, rhabdomyolysis was detected in one of them, while being seizure-free, suggesting that this adverse reaction may involve muscular tissue.

Original languageEnglish
Pages (from-to)1442-1444
Number of pages3
JournalNeurology
Volume49
Issue number5
DOIs
StatePublished - Nov 1997
Externally publishedYes

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