Motherisk - PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancy

Gideon Koren, Radinka Boskovic, Marjie Hard, Caroline Maltepe, Yvette Navioz, Adrienne Einarson

Research output: Contribution to journalArticlepeer-review

182 Scopus citations


OBJECTIVE: The morbidity of nausea and vomiting of pregnancy varies substantially. In addition to the physical symptoms, the emotional and psychosocial stress must be considered. The method available today to measure the severity of nausea and vomiting of pregnancy stems from chemotherapy-induced symptoms and is too complicated to use clinically. We sought to establish a simple and clinically relevant method for evaluation of the severity of nausea and vomiting of pregnancy that can be used for both clinical practice and research. METHODS: Women with nausea and vomiting of pregnancy were scored by use of the "gold standard" Rhodes' score, which includes 8 items. The Rhodes' score was compared with several short versions of 3 to 4 items. Patients were subsequently followed up a week later to monitor changes in scores. Changes in the Rhodes' scores were correlated with changes in the simplified scores. RESULTS: There was a very tight correlation between the Rhodes' score and the new pregnancy-unique quantification of emesis and nausea (PUQE) scoring system, which was based on the 3 items that included the number of daily vomiting episodes, the length of nausea per day in hours, and the number of retching episodes (r = 0.904; P < .0001). The distribution of severity of cases (between none, mild, moderate, and severe) did not differ between the Rhodes' and the PUQE. Comparing the changes in Rhodes' scores after a week of follow-up versus changes in the new PUQE score, there was a very high agreement (r = 0.95; P < .0001). CONCLUSION: The new PUQE score yields similar results to the gold standard, but more cumbersome, Rhode's score. Clinicians and researchers can easily use PUQE.

Original languageEnglish
Pages (from-to)S228-S231
JournalAmerican Journal of Obstetrics and Gynecology
Issue number5
StatePublished - 2002
Externally publishedYes


  • Nausea and vomiting of pregnancy
  • PUQE scoring system
  • Rhodes' score


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