TY - JOUR
T1 - Long-term neurodevelopmental risks in children exposed in utero to cocaine the toronto adoption study
AU - Koren, Gideon
AU - Nulman, Irena
AU - Rovet, Joanne
AU - Greenbaum, Rachel
AU - Loebstein, Michal
AU - Einarson, Tom
PY - 1998
Y1 - 1998
N2 - Children exposed in utero to cocaine are at risk for long-term neurobehavioral damage not just because of the drug itself, but also because of clustering of other health determinants, including low socioeconomic status, low maternal education, and maternal addiction, to mention a few. One methodologic approach to separate the direct neurotoxic effects of cocaine from these synergistic insults is to follow up a cohort of children exposed in utero to cocaine and given up for adoption to middle-upper class families. The Toronto Adoption Study, supported by Health Canada, has proven the direct neurotoxic effects of cocaine on IQ and language. These effects are mild to moderate as compared to those measured in children exposed in utero to cocaine and reared by their natural mothers.
AB - Children exposed in utero to cocaine are at risk for long-term neurobehavioral damage not just because of the drug itself, but also because of clustering of other health determinants, including low socioeconomic status, low maternal education, and maternal addiction, to mention a few. One methodologic approach to separate the direct neurotoxic effects of cocaine from these synergistic insults is to follow up a cohort of children exposed in utero to cocaine and given up for adoption to middle-upper class families. The Toronto Adoption Study, supported by Health Canada, has proven the direct neurotoxic effects of cocaine on IQ and language. These effects are mild to moderate as compared to those measured in children exposed in utero to cocaine and reared by their natural mothers.
UR - http://www.scopus.com/inward/record.url?scp=0031928261&partnerID=8YFLogxK
U2 - 10.1111/j.1749-6632.1998.tb09747.x
DO - 10.1111/j.1749-6632.1998.tb09747.x
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C2 - 9668417
AN - SCOPUS:0031928261
SN - 0077-8923
VL - 846
SP - 306
EP - 313
JO - Annals of the New York Academy of Sciences
JF - Annals of the New York Academy of Sciences
ER -