Laboratory evaluation of the CHROMagar KPC medium for identification of carbapenem-nonsusceptible Enterobacteriaceae

Jacob Moran Gilad; Yehuda Carmeli; David Schwartz; Shiri Navon-Venezia

doi:10.1016/j.diagmicrobio.2010.03.005

Laboratory evaluation of the CHROMagar KPC medium for identification of carbapenem-nonsusceptible Enterobacteriaceae

Jacob Moran Gilad, Yehuda Carmeli, David Schwartz, Shiri Navon-Venezia

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

CHROMagar KPC was evaluated with 53 carbapenem-nonsusceptible strains. KPC-producing Klebsiella pneumoniae and Enterobacter cloacae grew efficiently and yielded metallic blue colonies (100% sensitivity). Poor or no growth or atypical colony color were evident with KPC-producing Escherichia coli (71.4% sensitivity) and ertapenem-resistant KPC-nonproducing K. pneumoniae (72.7% sensitivity). CHROMagar KPC appears applicable for processing carbapenem-resistant Enterobacteriaceae surveillance specimens, but its performance might possibly be suboptimal in the presence of KPC-negative ertapenem-resistant strains or for detection of KPC-producing E. coli.

Original language	English
Pages (from-to)	565-567
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	70
Issue number	4
DOIs	https://doi.org/10.1016/j.diagmicrobio.2010.03.005
State	Published - Aug 2011
Externally published	Yes

Keywords

Antimicrobial
CHROMagar
Carbapenems
Enterobacteriaceae
Resistance

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10.1016/j.diagmicrobio.2010.03.005

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title = "Laboratory evaluation of the CHROMagar KPC medium for identification of carbapenem-nonsusceptible Enterobacteriaceae",

abstract = "CHROMagar KPC was evaluated with 53 carbapenem-nonsusceptible strains. KPC-producing Klebsiella pneumoniae and Enterobacter cloacae grew efficiently and yielded metallic blue colonies (100% sensitivity). Poor or no growth or atypical colony color were evident with KPC-producing Escherichia coli (71.4% sensitivity) and ertapenem-resistant KPC-nonproducing K. pneumoniae (72.7% sensitivity). CHROMagar KPC appears applicable for processing carbapenem-resistant Enterobacteriaceae surveillance specimens, but its performance might possibly be suboptimal in the presence of KPC-negative ertapenem-resistant strains or for detection of KPC-producing E. coli.",

keywords = "Antimicrobial, CHROMagar, Carbapenems, Enterobacteriaceae, Resistance",

author = "{Moran Gilad}, Jacob and Yehuda Carmeli and David Schwartz and Shiri Navon-Venezia",

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doi = "10.1016/j.diagmicrobio.2010.03.005",

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journal = "Diagnostic Microbiology and Infectious Disease",

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AU - Moran Gilad, Jacob

AU - Carmeli, Yehuda

AU - Schwartz, David

AU - Navon-Venezia, Shiri

PY - 2011/8

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AB - CHROMagar KPC was evaluated with 53 carbapenem-nonsusceptible strains. KPC-producing Klebsiella pneumoniae and Enterobacter cloacae grew efficiently and yielded metallic blue colonies (100% sensitivity). Poor or no growth or atypical colony color were evident with KPC-producing Escherichia coli (71.4% sensitivity) and ertapenem-resistant KPC-nonproducing K. pneumoniae (72.7% sensitivity). CHROMagar KPC appears applicable for processing carbapenem-resistant Enterobacteriaceae surveillance specimens, but its performance might possibly be suboptimal in the presence of KPC-negative ertapenem-resistant strains or for detection of KPC-producing E. coli.

KW - Antimicrobial

KW - CHROMagar

KW - Carbapenems

KW - Enterobacteriaceae

KW - Resistance

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Laboratory evaluation of the CHROMagar KPC medium for identification of carbapenem-nonsusceptible Enterobacteriaceae

Abstract

Keywords

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