J- vs. H-type assembly: Pentamethine cyanine (Cy5) as a near-IR chiroptical reporter

Larysa I. Markova; Vladimir L. Malinovskii; Leonid D. Patsenker; Robert Häner

doi:10.1039/c3cc42103a

J- vs. H-type assembly: Pentamethine cyanine (Cy5) as a near-IR chiroptical reporter

Larysa I. Markova
, Vladimir L. Malinovskii
, Leonid D. Patsenker
, Robert Häner

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

The DNA-enabled dimerization of pentamethine cyanine (Cy5) dyes was studied by optical methods. The value of cyanine as a chiroptical reporter using a monomer-to-dimer switch is demonstrated. The specific shape of the CD signal and its high intensity are a result of J-type assembly.

Original language	English
Pages (from-to)	5298-5300
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	46
DOIs	https://doi.org/10.1039/c3cc42103a
State	Published - 14 May 2013
Externally published	Yes

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10.1039/c3cc42103a

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abstract = "The DNA-enabled dimerization of pentamethine cyanine (Cy5) dyes was studied by optical methods. The value of cyanine as a chiroptical reporter using a monomer-to-dimer switch is demonstrated. The specific shape of the CD signal and its high intensity are a result of J-type assembly.",

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AU - Malinovskii, Vladimir L.

AU - Patsenker, Leonid D.

AU - Häner, Robert

PY - 2013/5/14

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AB - The DNA-enabled dimerization of pentamethine cyanine (Cy5) dyes was studied by optical methods. The value of cyanine as a chiroptical reporter using a monomer-to-dimer switch is demonstrated. The specific shape of the CD signal and its high intensity are a result of J-type assembly.

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U2 - 10.1039/c3cc42103a

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J- vs. H-type assembly: Pentamethine cyanine (Cy5) as a near-IR chiroptical reporter

Abstract

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