Induction of death of leukemia cells by tw-74, a novel derivative of chloro-naphthoquinone

Keyphrases

• Cell Death 100%
• Chloro 100%
• Leukemia Cells 100%
• Naphthoquinone 100%
• Apoptosis 66%
• B-CLL 66%
• Dose Effect 33%
• Anti-apoptotic Proteins 33%
• High Selectivity 33%
• Mitochondria 33%
• Mitochondrial Membrane Potential 33%
• Mononuclear Cells 33%
• Methyl Groups 33%
• B-cell Lymphoma 2 (Bcl-2) 33%
• Apoptosis Induction 33%
• Phenyl Ring 33%
• U937 33%
• Mitogen-activated Protein Kinase 33%
• U937 Cells 33%
• Early Reduction 33%
• Induced Cell Death 33%
• Caspase Activation 33%
• Cytochrome c Release 33%
• Structure-activity Relationship 33%
• Fast Activation 33%
• Intact Cells 33%
• Chronic Lymphocytic Leukemia Cells 33%
• Acute Myeloid Leukemia Cells 33%
• Myeloid Leukemia Cells 33%
• Isolated Rat Liver 33%
• Rat Liver Mitochondria 33%
• Cell Death Induction 33%
• Methyl Substitution 33%
• Monocytic Cells 33%
• 1-chloro-2 33%
• Relationship Research 33%
• 1,4-Naphthoquinone Derivatives 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Leukemia 100%
• Naphthoquinone 100%
• Methyl Group 66%
• Chronic Lymphatic Leukemia 66%
• Caspase 33%
• Antiapoptotic 33%
• Mitogen Activated Protein Kinase 33%
• Acute Myeloid Leukemia 33%
• Myeloid Leukemia 33%
• Cytochrome C 33%
• 1,4 Naphthoquinone Derivative 33%